Perfect Pass Probiotic: The Perfect Answer for Digestive Health?

This supplement is one of a few supplements marketed by Perfect Pass Vitamins and is affiliated with Dr. Pamela Nathan, who among other credentials is an acupuncturist, doctor of homeopathic medicine, board-certified Oriental Medicine practitioner and founder of www.Crohns.net. She is the founder of the Ecology Health Center in San Diego, CA.

What Probiotics are in Perfect Pass Probiotic?

This probiotic supplement contains 3 billion total cells per capsule of human-sourced strains of:

1. Bacillus subtilis HU58
2. Bacillus clausii
   
3. Bacillus coagulans

What are the Other Ingredients in Perfect Pass Probiotic? 

The other ingredient at the time of this writing is cellulose. Please verify ingredients of any supplement prior to taking it.

What is the Recommended Dosage of Perfect Pass Probiotic and for Which Conditions or Claims?

This supplement should be taken with food for best germination. The manufacturer’s dosage of this supplement is one capsule per day for adults and children over age 10. Children under 10 take one-half capsule per day which may be opened and added to food or drink. They also say that for “advanced use”, customers with chronic conditions may require 2 capsules per day.

What are the Pros of Perfect Pass Probiotic?

The pros of this probiotic supplement as I see them are:

• More than one species of Bacillus
• Compared to other multi-species Bacillus probiotic supplements, this one contains a high number of total CFU of 3 billion per capsule.
• Bacillus subtilis HU58 has some studies supporting it as a probiotic.
  
• Contains NO gluten, milk, wheat, soy, yeast, peanuts, corn or animal products.
• Other ingredients are limited to cellulose
• It is a vegetarian option
• It is shelf-stable

What Are the Cons of Perfect Pass Probiotic?

• Only Bacillus are included. Bacillus bacteria are a very small part of our microbiota and it takes a village of different types of bacteria to define gastrointestinal health.
• The marketing for this product is misleading. It says that “we have 20-30 trillion strains of lactobacillus and bifidus in our digestive tract” (which is a range far, far above what I have found in research) and that you can never take enough of them in pill or powder form to exceed that number so you have to take “loads of those strains” to achieve a beneficial effect. It also says that in order for those species to be recognized as therapeutic to the gut, they need to be human strain. This marketing is misleading because research shows that some people consuming a Western-style diet have NO Lactobacillus in their feces, and that for most people diet significantly affects those populations. Also, a person doesn’t have to take 20-30 trillion CFU to experience beneficial effects from Lactobacillus and Bifidobacterium, as many pages on this website show. Thirdly, probiotics do not have to colonize the GI tract to have beneficial effects.
• Only the species are given for 2 of the strains; you don't know which strains of those 2 species are in the product since the information is proprietary. Strain identification in Bacillus products is very important.
• Only the total CFU is given; you don't know how much of each species is present.
• It is not known if only endospores or endospores + vegetative cells are guaranteed to be in the product. The material says that the product contains endospores but does not show shelf-life to support that claim. Vegetative cells are not as resistant to stomach and bile acids and would result in reduced viability. I requested clarification of this from the company.
• No studies with this supplement as a whole supplement have been performed to my knowledge. Note that this is not unusual, however. Very few multi-species probiotic supplements are used in studies. Instead, species and strains that are show to be effective are mixed together in most multi-species supplements such as this one. Whether or not the strains compete with each other in a laboratory setting is not known since we don’t know which strains are in it.
• The studies that are referenced for the product may or may not actually contain the bacteria in this product and may or may not have them at the studied amounts.
• It is unknown if this supplement is produced in a GMP facility. I requested clarification of this from the company.
• It is unknown if this supplement is third-party tested for verification of strain identities and lack of contaminants in the finished product. I requested clarification of this from the company.
• It is unknown if potency is guaranteed through the expiration date. I requested clarification of this from the company.
• Sold only online on their website

Where to Find Perfect Pass Probiotic?

This particular combination of Bacillus species at this dosage is only found on the Perfect Pass Vitamins website. There are, however, other supplements with Bacillus subtilis HU58, Bacillus clausii and Bacillus coagulans bacteria such as MegaSporeBiotic.

Is Perfect Pass Probiotic the Right Supplement for YOU?

Bacillus subtilis HU58 is a fairly researched strain, but the other two strains are wild cards as to what effects they will have. While Bacillus species do contribute to the health of the gut, I do not believe that these three strains alone are the perfect answer for optimal digestive health by themselves. I recommend that you read the other website pages about Bacillus bacteria to guide you in your decision.

If you need any help in choosing probiotics for your situation, please consider nutritional consultations with me.

Thanks to Donna for suggesting a review of this supplement!

One Other Note

Since this product only contains Bacillus species, if you decide to take this supplement, I would combine the health benefits of it with the benefits provided by lactic acid bacteria such as Lactobacillus, Bifidobacterium and safe Streptococcus species. Many of those are found in:

• Fermented raw, whole foods and drinks
• Probiotic-fortified food and drinks
• Other probiotic supplements

Other Probiotic Supplement Reviews

To read about my approach to supplement reviews, and about my reviews of other probiotic supplements, click here.

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